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  • 2025

    The disposal of radioactive waste within the UK is managed through a comprehensive regulatory framework.This framework requires radioactive waste to be sufficiently well characterized to ensure its disposal is compliant with the regulations and the acceptance criteria for any receiving facility. This is the responsibility of both the waste consignor and the receiving facility.Characterization of solid radioactive waste is extremely challenging. This is due to the wastes exhibiting a high degree of heterogeneity which leads to significant uncertainty. Understanding the total uncertainty requires combining the uncertainties associated with numerous stages of the characterization process.Experience suggests that whilst uncertainties are included in waste characterization, approaches are variable in quality. This makes it challenging to present an appropriate level of confidence in the waste characterization and the subsequent decisions made to stakeholders.This paper introduces the concept and principles of uncertainty and uncertainty management in waste characterization, summarizing challenges, and gaps in the current approach. It recommends a solution is sought to address shortfalls in the understanding of uncertainty; identify sources of uncertainty across the whole characterization lifecycle; and agree how specialists might combine these uncertainties and communicate them to stakeholders.
    • Book : 57(1)
    • Pub. Date : 2025
    • Page : pp.1-7
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  • 2025

    In this work, a new Time Domain Random Walk (TDRW) algorithm is proposed to estimate the tracer distribution profile within the rock matrix. The development of the new algorithm stems from the statistical properties of the analytical solution to a single fracture-matrix system, in which the particle position at a certain time is calculated and recorded. With the position of each particle determined, the resulting distribution will then provide an estimate of the tracer distribution profile directly. In addition, the newly developed algorithm can readily be extended to a case of more complicated fracture-matrix system, in which an arbitrary injection boundary condition may also be used. To verify the accuracy and applicability of the new algorithm, three benchmark simulations are made, in which the results of different approaches are found to be identical. Nevertheless, the new algorithm has a higher computational efficiency, due to its lower calculation demand.
    • Book : 57(1)
    • Pub. Date : 2025
    • Page : pp.1-10
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  • 2025

    Gastric cancer is one of the most common cancers in both Korea and worldwide. Since 2004, the Korean Practice Guidelines for Gastric Cancer have been regularly updated, with the 4th edition published in 2022. The 4th edition was the result of a collaborative work by an interdisciplinary team, including experts in gastric surgery, gastroenterology, endoscopy, medical oncology, abdominal radiology, pathology, nuclear medicine, radiation oncology, and guideline development methodology. The current guideline is the 5th version, an updated version of the 4th edition. In this guideline, 6 key questions (KQs) were updated or proposed after a collaborative review by the working group, and 7 statements were developed, or revised, or discussed based on a systematic review using the MEDLINE, Embase, Cochrane Library, and KoreaMed database. Over the past 2 years, there have been significant changes in systemic treatment, leading to major updates and revisions focused on this area. Additionally, minor modifications have been made in other sections, incorporating recent research findings. The level of evidence and grading of recommendations were categorized according to the Grading of Recommendations, Assessment, Development and Evaluation system. Key factors for recommendation included the level of evidence, benefit, harm, and clinical applicability. The working group reviewed and discussed the recommendations to reach a consensus. The structure of this guideline remains similar to the 2022 version. Earlier sections cover general considerations, such as screening, diagnosis, and staging of endoscopy, pathology, radiology, and nuclear medicine. In the latter sections, statements are provided for each KQ based on clinical evidence, with flowcharts supporting these statements through meta-analysis and references. This multidisciplinary, evidence-based gastric cancer guideline aims to support clinicians in providing optimal care for gastric cancer patients.
    • Book : 25(1)
    • Pub. Date : 2025
    • Page : pp.5-114
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