All 3,276,462 Page 76/327,647
-
2025
- Book : ()
- Pub. Date : 2025
- Page :
- Keyword :
-
2025
- Book : ()
- Pub. Date : 2025
- Page : pp.101740-101740
- Keyword :
-
2025
Photocatalysts are the most essential in photocatalytic degradation of dyes in wastewater. Here, ZnO/TiO2 composite photocatalysts with variable proportions were prepared by chemical deposition method in order to meet the realistic requirements of low-cost synthesis, high stability, and environmental friendliness. The as-prepared photocatalyst was characterized by the technologies of scanning electron microscope, transmission electron microscope, X-ray photoelectron spectroscopy, Fourier-transform infrared spectroscopy, UV-vis diffuse reflection, photoluminescence spectroscopy, electrochemistry, nitrogen adsorption and X-ray diffraction. The degradation of methyl orange (MO) was applied to evaluate the photocatalytic activity of ZnO/TiO2 under low-power irradiation. At the same time, the effects of the chemical composition of photocatalyst, pH and MO concentration of solution on the photocatalytic degradation performance were mainly investigated. The results demonstrated an excellent synergistic effect between ZnO and TiO2 for improving the photocatalytic efficiency of the composite catalyst. The highest degradation rate of MO reaches to 98.6% for the photocatalyst with a mass proportion of ZnO:TiO2 being 0.131:1 under the condition of 10 mg/L for MO concentration and 6.7 for pH via the light of ultraviolet radiation A band. This study brings a new way for the production of low-cost and efficient catalysts with low-power light sources to mitigate azo dyes, e.g. MO. - Book : 108(1)
- Pub. Date : 2025
- Page :
- Keyword :
-
2025
The article presents the calculation of the structural and electronic characteristics of a conjugate consisting of the drug carboplatin (C6H12N2O4Pt) and a fullerenol (C60(OH)24) nanocarrier by the HF-3c method. Optimization of the geometric structure of the conjugate in an aqueous medium was carried out using the same level of theory and the polarizable continuum model. To clarify the nature of the intermolecular bond and assess the strength of the interaction between the carboplatin molecule and fullerenol, a topological analysis of the mechanisms of non-covalent interaction was performed based on the quantum theory of atoms in molecules. Individual paired atomic non-covalent interactions in the conjugate were analyzed and their energies were estimated using the correlation between the interaction energy and the characteristics of the electron density at the critical points of the bonds. It is shown that the conjugate is formed due to weak interaction forces between carboplatin and fullerenol, ensuring the release of the drug when delivering it to the corresponding DNA region without significant energy costs. The studied conjugates can be used for targeted drug delivery.- Book : 23(1)
- Pub. Date : 2025
- Page : pp.14-20
- Keyword :
-
2025
Melanoma brain metastases (MBM) remain a major therapeutic challenge, requiring a multidisciplinary approach integrating systemic and local therapies. The advent of immune checkpoint inhibitors and targeted therapies has markedly improved patients’ survival, with the combination of ipilimumab and nivolumab now considered as first-line systemic treatment for patients with asymptomatic MBM. Radiotherapy plays a crucial role, with stereotactic radiosurgery (SRS) now preferred over whole-brain radiotherapy (WBRT), due to its efficacy and lower risk of neurocognitive impairment. Retrospective data support a potential synergy between systemic therapy and SRS and emerging clinical evidence suggests that this combined approach may offer enhanced disease control and could become the standard of care. Key unresolved questions include the ideal sequencing of SRS with systemic treatments, the optimal radiation dose to balance efficacy and neuroprotection, and the identification of predictive biomarkers to refine patient selection. Emerging research focuses on tumor microenvironment interactions and novel radiosensitizers to enhance therapeutic outcomes. Furthermore, artificial intelligence-driven models integrating radiomics, radiogenomics, and metabolomics hold promise for advancing precision medicine in MBM management. Ongoing prospective clinical trials are crucial to establishing standardized treatment guidelines, ensuring a personalized, patient-centered approach that optimizes survival while preserving quality of life.- Book : ()
- Pub. Date : 2025
- Page :
- Keyword :
-
2025
Retrieving LST from infrared spectral observations is challenging because it needs separation from emissivity in surface radiation emission, which is feasible only when the state of the surface–atmosphere system is known. Thanks to its high spectral resolution, the Infrared Atmospheric Sounding Interferometer (IASI) instrument onboard Metop polar-orbiting satellites is the only sensor that can simultaneously retrieve LST, the emissivity spectrum, and atmospheric composition. Still, it cannot penetrate thick cloud layers, making observations blind to surface emissions under cloudy conditions, with surface and atmospheric parameters being flagged as voids. The present paper aims to discuss a downscaling–fusion methodology to retrieve LST missing values on a spatial field retrieved from spatially scattered IASI observations to yield level 3, regularly gridded data, using as proxy data LST from the Spinning Enhanced Visible and Infrared Imager (SEVIRI) flying on Meteosat Second Generation (MSG) platform, a geostationary instrument, and from the Advanced Very High-Resolution Radiometer (AVHRR) onboard Metop polar-orbiting satellites. We address this problem by using machine learning techniques, i.e., Gradient Boosting, Random Forest, Gaussian Process Regression, Neural Network, and Stacked Regression. We applied the methodology over the Po Valley region, a very heterogeneous area that allows addressing the trained models’ robustness. Overall, the methods significantly enhanced spatial sampling, keeping errors in terms of Root Mean Square Error (RMSE) and bias (Mean Absolute Error, MAE) very low. Although we demonstrate and assess the results primarily using IASI data, the paper is also intended for applications to the IASI follow-on, that is, IASI Next Generation (IASI-NG), and much more to the Infrared Sounder (IRS), which is planned to fly this year, 2025, on the Meteosat Third Generation platform (MTG).- Book : 17(4)
- Pub. Date : 2025
- Page : pp.694-694
- Keyword :
-
2025
- Book : 1074()
- Pub. Date : 2025
- Page : pp.170310-170310
- Keyword :
-
2025
Abstract
This study presents an analysis of a point absorber wave energy converter (WEC) system, employing advanced numerical modeling and time-domain simulations to evaluate and optimize the device’s performance. The wave energy converter consists of a single floating body coupled with a spring-mass damper system. Buoys with different drafts are analyzed to maximize the energy absorption of the wave energy converter. The numerical examples in this work were implemented using the boundary element method via the ANSYS Aqwa software. The hydrodynamic parameters analyzed in the paper include excitation force, added mass, radiation damping coefficient, response amplitude operator (RAO), and the wave energy absorption power of the buoy. From the obtained results, the hydrodynamic behavior characteristics, overall cost optimization, and power absorption of buoys with different drafts can be evaluated to ensure their energy absorption.- Book : 2949(1)
- Pub. Date : 2025
- Page : pp.012047-012047
- Keyword :
-
2025
Introduction: Allogeneic stem cell transplantation (allo-HCT) involves a long trajectory with high risk of complications. In person-centred care (PCC), patients’ needs, resources and the care relationship are central to the care process. Healthcare professionals’ (HCPs) ratings of PCC have not previously been investigated in this context. Objectives: The aim of this study was to investigate healthcare professionals’ ratings and views of person-centred care in allo-HCT care, and associations with individual characteristics and targeted PCC education. Design: Cross-sectional study, employing quantitative and qualitative methods. Methods: 85 HCPs at two Swedish allo-HCT centres participated (80% women; mean age: 44 years, range: 23-72 years). A survey was conducted using the PCC Assessment Tool (P-CAT), containing 13 items, a total scale (min 13-max 65) and two subscales (I: min 8-max 40; II: min 5-max 25). Additionally, HCPs’ written responses to four study-specific questions about PCC were collected. Results: The mean for P-CAT total scale was 45.31, (subscale I: 28.41; subscale II: 16.90). Higher ratings of PCC were reported for assessment of patients’ needs, discussion about how to provide PCC and patients’ care, while time to provide PCC, the care environment and how the organization prevents providing PCC were rated lower. Higher age and targeted PCC education were associated with higher PCC ratings. HCPs described PCC as the patient being seen as a capable individual with their own resources, with PCC increasing patient and family involvement—giving higher satisfaction and tailored care for patients. However, HCPs reported time as a barrier for PCC. Conclusion: HCPs’ ratings of PCC in this context are high regarding discussing and assessing patients’ needs, but there is room for improvement regarding organizational and environmental aspects. Targeted PCC education increases the level of PCC. HCPs’ views of PCC partly reflect the foundations of PCC—patient’s narrative, capability and involvement. - Book : 18()
- Pub. Date : 2025
- Page :
- Keyword :
-
2025
- Book : ()
- Pub. Date : 2025
- Page :
- Keyword :
