Various implementations described herein relate to synthetic nuclear tags for delivering various agents to the nucleus of a cell. The synthetic nuclear tags include a polyarginine linker attached to a bipartite nuclear localization signal (NLS). According to some implementations, a detectable label linked to the synthetic nuclear tag is administered to a subject or a sample, and an imaging device is used to detect the detectable label. Particular implementations include a construct encoding the synthetic nuclear tag and an agent. An example method includes administering a therapeutic agent linked to the synthetic nuclear tag to a subject. Example methods and compositions described herein can be used for diagnostic, therapeutic, or research purposes.

• 출원번호 : US2024/029476
• 출원인 : UNIVERSITY OF WASHINGTON
• 특허번호 :
• IPC :

The present invention concerns a system for classifying a cataract. The system comprises a head positioning module (100) suitable for receiving a head of a patient and positioning it, a source module (201) capable of emitting electromagnetic radiation, with a frequency between 400nm and 490nm, and preferably between 450nm and 470nm and more preferably equal to 460nm, to focus it on a lens of the patient and a detector module (202) suitable for acquiring the image of the lens illuminated by electromagnetic radiation. A control unit (204) configured to control the source module (201) and the detector module (202), and to process the lens image to determine the grade of cataract based on pixel values of the image. A computerized method for classifying a cataract is also described.

• 출원번호 : IB2024/054719
• 출원인 : OSPEDALE SAN RAFFAELE S.R.L.
• 특허번호 :
• IPC : A61B-003/10(2006.01);A61B-003/117(2006.01);G06T-007/00(2017.01);

An optoelectronic semiconductor chip comprises a front-side radiation-transmissive chip substrate, a rear-side semicon- ductor layer sequence arranged on the chip substrate, the semiconductor layer sequence being configured for radiation emission or radiation detection, and rear-side contact elements for contacting the semiconductor layer sequence. The chip substrate is formed in one piece with a lens shape deviating from a cuboid shape. Further described is a method for producing at least one optoelectronic semiconductor chip.

• 출원번호 : EP2024/063380
• 출원인 : AMS-OSRAM INTERNATIONAL GMBH
• 특허번호 :
• IPC : H01L-033/58(2010.01);H01L-031/0232(2014.01);H01L-033/44(2010.01);H01L-033/46(2010.01);H01L-033/48(2010.01);

The invention relates to a LIDAR system (10) comprising a tunable laser source (100) suitable for emitting electromagnetic radiation, namely source radiation (15), which is reflected by an object (105). The LIDAR system (10) also comprises a multi-mode waveguide (112) suitable for receiving radiation (16) reflected by the object (105), and a plurality of single-mode waveguides (1151, 1152, …115n) and a coupling device (118, 132) suitable for supplying each of the modes (161, 162) of the reflected radiation (16) that have been guided through the multi-mode waveguide (112) to one of the single-mode waveguides (1151, 1152, …115n). The LIDAR system also comprises a plurality of detection devices (125) each suitable for detecting a heterodyne signal resulting from the reflected radiation (16) that has been guided through an associated single-mode waveguide (1151, 1152, …115n) heterodyning a partial beam of the source radiation (15).

• 출원번호 : EP2024/063413
• 출원인 : AMS-OSRAM INTERNATIONAL GMBH
• 특허번호 :
• IPC : G01S-007/481(2006.01);G01S-017/34(2020.01);G01S-007/4912(2020.01);

Provided in the present invention is an antenna, which comprises a dielectric substrate, a first dipole antenna and a second dipole antenna, wherein the dielectric substrate has a first surface and a second surface which are oppositely arranged in the direction of thickness of the dielectric substrate; the first dipole antenna comprises a first radiation part arranged on the first surface, a second radiation part arranged on the second surface, and a first feeder electrically connected to the first radiation part and the second radiation part; and the second dipole antenna comprises a third radiation part arranged on the first surface, a fourth radiation part arranged on the second surface, and a second feeder electrically connected to the third radiation part and the fourth radiation part. Each of the first radiation part, the second radiation part, the third radiation part and the fourth radiation part comprises a main body structure and an auxiliary structure, wherein the main body structure has an opening; and the auxiliary structure is arranged in the opening and is electrically connected to the main body structure.

• 출원번호 : CN2024/093359
• 출원인 : BOE TECHNOLOGY GROUP CO., LTD.;BEIJING BOE TECHNOLOGY DEVELOPMENT CO., LTD.;
• 특허번호 :
• IPC : H01Q-009/16(2006.01)

A system and methods for integrating a small modular nuclear reactor into a steam cracking process are provided. An exemplary system provides a steam cracking system that includes a small modular reactor (SMR) to provide a heat exchange stream and a steam heat exchanger to use the heat exchange stream to generate a steam stream from a water stream, wherein the steam stream is provided to a steam-cracking furnace. A feed heat exchanger uses the heat exchange stream to generate a hot feed stream, wherein the hot feed stream is provided to the steam -cracking furnace. The steam -cracking furnace to generate a product stream including an olefin.

• 출원번호 : IB2024/054738
• 출원인 : NOVA CHEMICALS (INTERNATIONAL) S.A.
• 특허번호 :
• IPC : C10G-009/36(2006.01);G21C-001/32(2006.01);

A seed laser system for an EUV radiation source, the seed laser system comprising a laser configured to emit a pulsed laser beam, at least one electro-optic modulator located downstream of the laser, and an optical amplifier located downstream of the at least one electro-optic modulator, wherein the seed laser system further comprises an additional electro-optic modulator located downstream of the optical amplifier.

• 출원번호 : EP2024/063367
• 출원인 : ASML NETHERLANDS B.V.;TRUMPF LASERSYSTEMS FOR SEMICONDUCTOR MANUFACTURING GMBH;
• 특허번호 :
• IPC : H01S-003/00(2006.01);H01S-003/10(2006.01);H01S-003/107(2006.01);H01S-003/23(2006.01);H01S-003/223(2006.01);

A radiation source assembly for generating broadband radiation. The radiation source assembly comprises a gas cell enclosing a hollow core fiber, wherein the gas cell comprises an input port arranged to receive pump radiation, and an output port arranged to output the broadband radiation, wherein the gas cell and a hollow core of the hollow core fiber is filled with a gas composition. The radiation source assembly further comprises at least one getter provided within the gas cell and at least partially surrounded by the gas composition, wherein the hollow core fiber is arranged to receive the pump radiation at an input end of the hollow core fiber, and output the broadband radiation at an output end of the hollow core fiber.

• 출원번호 : EP2024/063306
• 출원인 : ASML NETHERLANDS B.V.
• 특허번호 :
• IPC : G02F-001/35(2006.01);G02F-001/365(2006.01);

The present invention relates to an aerosol generation device and a microwave heating assembly thereof. The microwave heating assembly comprises: an outer conductor unit, which comprises a closed end, an open end and a cavity; an inner conductor unit, which is arranged in the cavity and comprises a radiation structure and an inner conductor body; an accommodating seat, which is connected to the open end and comprises an accommodating cavity located in the cavity; and a sealing seat, which is cylindrical and is arranged between the inner conductor body and the accommodating seat, and comprises a sealing side wall configured to reduce the generation of condensate in a heating process. The radiation structure passes through the sealing seat and the accommodating seat and extends into the accommodating cavity. The aerosol generation device comprises a microwave generation unit and the microwave heating assembly. In the present invention, the sealing seat and the accommodating seat are in interference fit with the radiation structure to form a dual sealing structure, so that the generation of condensate can be effectively reduced, and the generated condensate is prevented from entering the cavity, thereby reducing the forming of condensate and the contamination of the cavity, and improving the use reliability of the cavity.

• 출원번호 : CN2024/093503
• 출원인 : SMOORE INTERNATIONAL HOLDINGS LIMITED;SHENZHEN SMOORE TECHNOLOGY LIMITED;
• 특허번호 :
• IPC : A24F-040/05(2020.01);A24F-040/20(2020.01);A24F-040/40(2020.01);H05B-006/64(2006.01);H05B-006/72(2006.01);

A treatment device for the surgical correction of hyperopia in the eye comprising a laser device controlled by a control device. The laser device separating corneal tissue by applying laser radiation. The control device controls the laser device for emitting the laser radiation into the cornea such that a lenticule-shaped volume is isolated. Removal thereof effects the desired correction. The control device predefines the volume such that a posterior surface and an anterior surface are connected via an edge surface that has a width in projection along the visual axis that is wider than the one which a straight line in the same projection, that is perpendicular at the edge of the posterior or the anterior surface would have relative to the associated surface and connects the anterior surface to the posterior surface or to the perceived extension thereof.

• 출원번호 : 18665313
• 출원인 : Bischoff, Mark
• 특허번호 :
• IPC : A61F-009/008(2006.01);A61B-034/10(2006.01);H01S-003/00(2006.01);