Systems and methods for improved radiation treatment planning can employ hierarchical constrained optimization with relaxed constraints also referred to herein after as expedited hierarchical constrained optimization (ECHO). The systems and methods described herein employ a combination of constrained optimization and a correction loop involving unconstrained optimization to enhance the speed and efficiency of the radiation treatment planning process and improve the accuracy and quality of resulting radiation treatment plans. The use of a hierarchical constrained optimization approach leads to less complex and faster to solve optimization problems. The correction loop allows for compensating for optimization error associated with the sequence of constrained optimizations by incorporating such error in an unconstrained optimization. Hard and soft dose volume constraints can be efficiently incorporated.

• 출원번호 : 18828870
• 출원인 : ZAREPISHEH, Masoud
• 특허번호 :
• IPC : A61N-005/10(2006.01)

Systems and methods for imaging in the short wave infrared (SWIR), photodetectors with low dark current and associated circuits for reducing dark currents and methods for generating image information based on data of a photodetector array. A SWIR imaging system may include a pulsed illumination source operative to emit radiation pulses in the SWIR band towards a target resulting in reflected radiation from the target; (b) an imaging receiver including a plurality of Ge PDs operative to detect the reflected SWIR radiation and a controller, operative to control activation of the receiver for an integration time during which the accumulated dark current noise does not exceed the time independent readout noise.

• 출원번호 : 18827906
• 출원인 : Prosper Shalibo, Yoni
• 특허번호 :
• IPC : H01S-005/06(2006.01);B32B-018/00(2006.01);C04B-035/495(2006.01);G01S-007/484(2006.01);H01S-003/06(2006.01);H01S-003/0941(2006.01);H01S-003/113(2006.01);H01S-003/131(2006.01);H01S-003/16(2006.01);H01S-005/00(2006.01);

Provided are a high-purity styrenesulfonic acid compound having a markedly decreased amount of bonded bromine and a polymer thereof, which are useful for modifiers for secondary batteries, dopants for conductive polymers, additives for semiconductor polishing and cleaning agents, organic EL elements, and photoresists, and particularly for members for electronic materials. A high-purity 4-(2-bromoethyl)benzenesulfonic acid having a decreased amount of nuclear-brominated forms, a high-purity styrenesulfonic acid compound having a markedly decreased amount of bonded bromine, which are derived from the high-purity 4-(2-bromoethyl)benzenesulfonic acid, and a polymer of the high-purity styrenesulfonic acid compound are used.

• 출원번호 : 18828269
• 출원인 : TOSOH FINECHEM CORPORATION
• 특허번호 :
• IPC : C08F-112/08(2006.01);C07C-303/06(2006.01);C07C-311/15(2006.01);

The system and method provided herein is an interactive computer based graphical user interface that permits a user to dynamically assemble, and process, spatially contoured (segmented) anatomical structures shown on medical images for radiation treatment planning. The generation of planning structures utilizing node-based operations based on contoured organs is a critical part of the radiation therapy planning workflow. The overall goal is to optimize the plan for treatment and deliver a precise dose of radiation to a target (typically a tumor) while minimizing radiation exposure to surrounding healthy tissues.

• 출원번호 : 18828832
• 출원인 : Otto, Karl
• 특허번호 :
• IPC : A61N-005/10(2006.01);G16H-020/40(2006.01);G16H-030/40(2006.01);

In order to estimate a radiation load quantity for an imaging system having a radiation source, a base model is obtained for determining the radiation load quantity depending on a set of input variables, which include at least one radiation-source operating parameter. Measurement data measured for the imaging system is obtained that includes the radiation load quantity for a multiplicity of different values of the at least one radiation-source operating parameter. A refined model is generated by adapting the base model depending on the measurement data. Actual values of the set of input variables are defined for the imaging system. The refined model is used to determine, depending on the actual values of the set of input variables, an estimated value of the radiation load quantity.

• 출원번호 : 18828470
• 출원인 : Birkhold, Annette
• 특허번호 :
• IPC : G01T-001/02(2006.01);G06N-020/00(2019.01);

Disclosed herein are methods of treatments with a telomerase-mediated telomere-targeting drug, 6-thio-2′-deoxyguanosine (6-thio-dG), checkpoint inhibitors and/or radiation therapy for treating cancers. eads to tumor regression in innate and adaptive immune-dependent manners in syngeneic and humanized mouse cancer models.

• 출원번호 : 18829162
• 출원인 : The Board of Regents of The University of Texas System
• 특허번호 :
• IPC : A61K-031/7076(2006.01);A61N-005/00(2006.01);A61P-035/00(2006.01);C07K-016/28(2006.01);

A sensor including a light-receiving element; and an optical element that includes near infrared absorbing dichroic substance. The optical element has an absorption axis with respect to near infrared light in an in-plane direction. When linearly polarized light of near infrared light orthogonal to the absorption axis is radiated from a normal direction of the optical element and from a direction inclined by 45° from the normal direction at an azimuthal angle orthogonal to the absorption axis, an absorbance during the radiation from the direction inclined by 45° from the normal direction is more than an absorbance during the radiation from the normal direction.

• 출원번호 : 18828794
• 출원인 : FUJIFILM Corporation
• 특허번호 :
• IPC : G06V-040/13(2006.01);G02B-005/20(2006.01);

• 출원번호 : CN2024/117685
• 출원인 : SHANGHAI NUCLEAR ENGINEERING RESEARCH &DESIGN INSTITUTE CO., LTD.;
• 특허번호 :
• IPC : G21C-015/18(2006.01)

Apparatus, systems, and methods are provided for optimizing radiation therapy to a patient to treat cardiac arrhythmias. The system generally includes an ultrasound device placed within the esophagus to image and map cardiac structures in real-time. The system may also control the ventilation of the patient to optimize ultrasound monitoring and radiation delivery. The device in the esophagus is designed to position and monitor the esophagus and/or nearby structures to optimize radiation delivery to targets while minimizing radiation to other key structures. In addition, different ablation technologies may be delivered from within the esophagus to ablate certain tissues that cannot be safely ablated with radiation therapy. Finally, the esophageal device may have electrical or magnetic properties that can be used to guide the radiation therapy.

• 출원번호 : 18828736
• 출원인 : Kaiser, Daniel Walter
• 특허번호 :
• IPC : A61B-018/14(2006.01);A61B-008/06(2006.01);A61B-008/08(2006.01);A61B-008/12(2006.01);A61B-018/00(2006.01);

Systems and methods for positioning in medical systems are provided. The system may obtain data associated with a scanning range of a subject. The system may also obtain an image of the subject on a couch of a medical radiation device. The image may be acquired by an imaging device when the couch is at a first position. The system may determine a position of the scanning range of the subject in the image. The system may further cause, based on the position of the scanning range in the image, the couch to move to a second position. The scanning range of the subject may be in a radiation region of the medical radiation device when the couch is located at the second position.

• 출원번호 : 18827885
• 출원인 : SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.
• 특허번호 :
• IPC : A61B-006/04(2006.01);A61B-005/055(2006.01);A61B-006/00(2006.01);A61B-006/46(2006.01);A61B-006/58(2006.01);G06F-003/0482(2006.01);G06F-003/04847(2006.01);G06T-007/00(2006.01);G06T-007/50(2006.01);G06T-007/70(2006.01);