The present disclosure provides, according to some embodiments, methods and systems for selectively reducing, blocking or inhibiting at least part of the neural activity in an organ of a subject. In preferred embodiments, the method and system are used for selectively blocking at least part of the neural activity in a duodenum of a subject in need thereof. According to some embodiments, the selective blocking occurs through use of laser radiation. According to some embodiments, the selective blocking comprises causing damage to at least part of sensory nerves located within a target area while maintaining functional activity of tissue surrounding the sensory nerves. According to some embodiments, the sensory nerves include neurons configured to transmit signals triggered by food passing through the duodenum, such as, but not limited to, neurohormonal signals.

• 출원번호 : 18944543
• 출원인 : BEN-OREN, Ilan
• 특허번호 :
• IPC : A61B-018/24(2006.01);A61B-018/00(2006.01);A61B-018/20(2006.01);A61B-018/22(2006.01);A61N-007/00(2006.01);

The disclosure provides a method for correcting higher-order aberrations including providing a laser radiation. The method also includes controlling a location of a beam focal point of the laser radiation by a system of scanners and guiding the beam focal point in such a way that the location of the beam focal point is in a cornea of an eye. The method further includes introducing the laser radiation into the cornea of the eye. The method includes cutting a lenslet, wherein a thickness of the lenslet t(X,Y) satisfies a following equation: t(X,Y)=t0+Δt(X,Y)/(n−1), where Δt(X,Y) represents a higher-order wavefront elevation and t0 represents the thickness of the lenslet having a spherical refractive power of D.

• 출원번호 : 18943071
• 출원인 : HEGEDUS, Imre
• 특허번호 :
• IPC : A61F-009/008(2006.01)

Methods of making a thermoset thermal energy gels, such as one having a radiation cured polymeric network, are disclosed. The methods include providing a hydrophobic PCM in its liquid state, adding a polybutadiene urethane acrylate oligomer and a mono-functional or di-functional crosslinker soluble in the hydrophobic PCM to the hydrophobic PCM while maintaining the liquid state of the hydrophobic phase change material to form a liquid homogenous mixture, then adding a photoinitiator, which is soluble in the hydrophobic PCM, with mixing to form a final mixture. Next, curing the final mixture occurs by exposure to radiation to form the thermoset thermal energy gel.

• 출원번호 : 18942953
• 출원인 : MICROTEK LABORATORIES, INC.
• 특허번호 :
• IPC : C08G-018/81(2006.01);A61F-007/02(2006.01);C08G-018/69(2006.01);C08K-005/01(2006.01);C08K-005/3412(2006.01);C08K-005/5397(2006.01);C08L-053/02(2006.01);C09K-005/06(2006.01);

A method for producing a reinforcement rod from a fibrous composite material comprising continuous mineral fibers and at least one resin, the resin being mixed with the dry mineral fibers, then wrapped with a strand of material, and the resin then being instantaneous or nearly instantaneously fully cured (e.g., snap cured) to form an optionally round rod with an optionally helical rib. In aspects, a mixture comprising an environmentally friendly and zero or low volatile organic compound (VOC) emitting resin and a resin-curing agent mixture is used. In aspects, helical ribs are added to the surface of the rod in a manner not to disrupt the longitudinal orientation of the core reinforcing mineral fibers. In aspects, ultraviolet irradiators are used to snap cure the reinforcement. When fully cured, corrosion resistant mineral fibers are encapsulated in a corrosion resistant matrix. The process allows for a simplified, condensed, and single operation for producing a corrosion resistant fibrous composite reinforcement rod.

• 출원번호 : 18943036
• 출원인 : Sorensen, Joe
• 특허번호 :
• IPC : B29C-070/52(2006.01);B29L-031/06(2006.01);

The present disclosure provides methods, systems, and devices for coregistering imaging data to form three-dimensional superimposed images of a biological target such as a wound, a tumor, or a surgical bed. A three-dimensional map can be generated by projecting infrared radiation at a target area, receiving reflected infrared radiation, and measuring depth of the target area. A three-dimensional white light image can be created from a captured two-dimensional white light image and the three-dimensional map. A three-dimensional fluorescence image can be created from a captured two-dimensional fluorescence image and the three-dimensional map. The three-dimensional white light image and the three-dimensional fluorescence image can be aligned using one or more fiducial markers to form a three-dimensional superimposed image. The superimposed image can be used to track wound healing and to excise cancerous tissues, for example, breast tumors. Images can be in the form of videos.

• 출원번호 : 18943247
• 출원인 : UNIVERSITY HEALTH NETWORK
• 특허번호 :
• IPC : G06T-007/00(2006.01);A61B-005/00(2006.01);G06T-007/33(2006.01);G16H-030/40(2006.01);

Various examples disclosed relate to a method of manufacturing a mechanically stabilized material that includes a nanostructure. The method includes providing a curable material disposed on a substrate. The curable material includes inorganic nanoparticles. The method further includes exposing the curable material and the substrate to pulsed electromagnetic radiation to form the mechanically stabilized material.

• 출원번호 : 18942155
• 출원인 : Watkins, James J.
• 특허번호 :
• IPC : G03F-007/00(2006.01);H01M-004/04(2006.01);H01M-006/40(2006.01);

Disclosed are embodiments of polymer compositions and systems that contain antimicrobial and wavelength-shifting metal nanoparticles. The polymer compositions containing metal nanoparticles protect exposed materials from UV radiation. The polymer compositions containing metal nanoparticles down convert incoming UV light to light that may have a longer wavelength. Unexpectedly, by selecting at least two differently configured nanoparticle components (e.g., different in size, shape, or both), each with specific particle size distribution, it is possible to effectively protect an area from damage resulting from exposure to UV radiation. In addition, spherical silver nanoparticles do not cause bacteria to become resistant as do convention silver nanoparticles made by chemical synthesis. Polymer compositions can be made from thermoplastic and thermoset materials.

• 출원번호 : 18942231
• 출원인 : Niedermeyer, William H.
• 특허번호 :
• IPC : C08J-003/12(2006.01);C08J-003/20(2006.01);C08K-003/08(2006.01);C08K-007/18(2006.01);

A method of treating teeth includes applying an oral care article to at least one tooth, maintaining the oral care article on the at least one tooth for a first period of time, and, after the first period of time, directing a light radiation toward the at least one tooth for a second period of time, the first period of time having a duration greater than 50% of a total duration of the first period of time and the second period of time. The oral care article includes a solid water insoluble delivery carrier and solid hydrophilic particles embedded in the solid water insoluble delivery carrier partially below the first surface and partially at or above the first surface of the solid hydrophobic delivery carrier.

• 출원번호 : 18941686
• 출원인 : SAGEL, Paul Albert
• 특허번호 :
• IPC : A61K-008/02(2006.01);A61K-008/22(2006.01);A61K-008/81(2006.01);A61Q-011/00(2006.01);

본 출원은 방사선 치료의 적어도 하나의 선량 및 적어도 하나의 PD-1 및/또는 PD-L1 길항제를 투여하는 단계를 포함하는, 환자에서의 암 치료 방법을 제공하며, 여기서 적어도 하나의 PD-1 및/또는 PD-L1 길항제는 방사선 치료 선량투여와 동일한 날 또는 이후 최대 4일까지를 포함해서 투여된다.

• 출원번호 : 10-2024-7037128
• 출원인 : 메디뮨 리미티드
• 특허번호 :
• IPC : A61K-039/395;A61K-039/00;A61N-005/10;A61P-035/00;A61P-035/02;C07K-016/28;

A germ decontamination apparatus includes an enclosure including an access door configurable to be in an open or closed position, an opening for positioning the enclosure over or around a fomite, opening means for opening the access door in response to a trigger or triggering event, one or more ultraviolet light sources disposed inside the enclosure and configured to decontaminate the fomite. The germ decontamination apparatus may include one or more sensors configured to detect a triggering event. The one or more sensors may include an obstruction sensor, a motion sensor or detector, a light sensor, a sound sensor, and/or a heat or infrared sensor. The access door may include one or more access panels. The one or more ultraviolet light sources may produce UV-C radiation with a wavelength in the range of 200-280 nm. Methods of use and systems comprising the germ decontamination apparatus are also provided.

• 출원번호 : 18940590
• 출원인 : Microlumix LLC
• 특허번호 :
• IPC : A61L-002/10(2006.01);A61L-002/24(2006.01);