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  • 2025


    • Book : ()
    • Pub. Date : 2025
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  • 2025


    • Book : ()
    • Pub. Date : 2025
    • Page : pp.100745-100745
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  • 2025


    • Book : 3()
    • Pub. Date : 2025
    • Page : pp.102330-102330
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  • 2025

    Abstract Space infrared cameras perform non-uniformity correction of detectors through on-board calibration in orbit. Using the blackbody component inside the camera as a standard radiation source is a commonly used method. As the accuracy of calibration increases, there are also high requirements for the temperature stability and uniformity of the blackbody inside the camera. This article addresses the problem of thermal control of large-scale internal black bodies and proposes a hybrid temperature control method that relies primarily on radiation and is supplemented by thermal conduction. By modulating the thermal resistance of thermal conduction, the influence ratio of radiation and thermal conduction can be adjusted to ensure control capability while maximizing the temperature uniformity of the controlled black body. After flight verification, the blackbody temperature stability can reach ±0.1K, and the temperature uniformity can reach 0.2K, meeting the calibration accuracy requirements of remote sensing imaging. This article improves the traditional blackbody control scheme that relies solely on temperature control algorithms, introducing active and passive thermal control measures to meet the new requirements of large-scale blackbodies. The scheme adopted can provide a reference for temperature control of large-scale surface source blackbody.
    • Book : 2977(1)
    • Pub. Date : 2025
    • Page : pp.012067-012067
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  • 2025

    ABSTRACTBackground and AimsTropical plants are assumed to be especially vulnerable to global warming because their physiologies are adapted to relatively constant temperatures throughout the year. Furthermore, it has been found that woody plants in colder high elevation environments are less tolerant to high temperatures than plants in the warmer lowlands. Here, we examined heat tolerance in a group of herbaceous plants with a wide elevational distribution in the tropics.MethodsThis study focused on 61 species from the order Zingiberales (ginger and banana-like plants) distributed from the lowlands (50 m asl) to lower montane forests (2000 m asl) along the Barva elevational gradient in Costa Rica.This study addressed the following questions:a)Does heat tolerance of Zingiberales species differ along the elevational gradient?b)Does heat tolerance vary along the elevational gradient within families of Zingiberales?c)Does heat tolerance vary along the elevational gradient within species for those with broad elevational distributions? To test if the temperature that causes damage to the function of photosystem II (PSII) in Zingiberales is associated with the temperatures prevalent at their elevation, we estimated heat tolerance (T50) of PSII using chlorophyll fluorescence techniques.Key ResultsIn contrast to the results found in tropical trees, our results showed that T50is higher at higher elevations than in the lowlands for herbaceous plants species. This trend was observed across plant communities and families, and within most species with wide distributions along the elevational gradient.ConclusionsOur study suggests that herbs differ from trees in their elevational patterns in heat tolerance. We hypothesize that maximum and minimum leaf temperatures, and UV radiation may play a role in the observed pattern.
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    • Pub. Date : 2025
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  • 2025

    Over 64 million people worldwide are affected by heart failure (HF), a condition that significantly raises mortality and medical expenses. In this study, we explore the potential of retinal optical coherence tomography (OCT) features as non-invasive biomarkers for the classification of heart failure subtypes: left ventricular heart failure (LVHF), congestive heart failure (CHF), and unspecified heart failure (UHF). By analyzing retinal measurements from the left eye, right eye, and both eyes, we aim to investigate the relationship between ocular indicators and heart failure using machine learning (ML) techniques. We conducted nine classification experiments to compare normal individuals against LVHF, CHF, and UHF patients, using retinal OCT features from each eye separately and in combination. Our analysis revealed that retinal thickness metrics, particularly ISOS-RPE and macular thickness in various regions, were significantly reduced in heart failure patients. Logistic regression, CatBoost, and XGBoost models demonstrated robust performance, with notable accuracy and area under the curve (AUC) scores, especially in classifying CHF and UHF. Feature importance analysis highlighted key retinal parameters, such as inner segment-outer segment to retinal pigment epithelium (ISOS-RPE) and inner nuclear layer to the external limiting membrane (INL-ELM) thickness, as crucial indicators for heart failure detection. The integration of explainable artificial intelligence further enhanced model interpretability, shedding light on the biological mechanisms linking retinal changes to heart failure pathology. Our findings suggest that retinal OCT features, particularly when derived from both eyes, have significant potential as non-invasive tools for early detection and classification of heart failure. These insights may aid in developing wearable, portable diagnostic systems, providing scalable solutions for personalized healthcare, and improving clinical outcomes for heart failure patients.
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    • Pub. Date : 2025
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  • 2025

    AbstractPurposeDue to the tight curvature in their design, ring applicators are usually associated with large positioning errors. The standard practice to correct for these deviations based on global offsets may not be sufficient to comply with the recommended tolerance. In this work, we investigate two methods for applicator reconstruction that implement position‐dependent source offset corrections.MethodsMeasurements were performed using the Varian Interstitial PEEK Ring 60° and a Varian BRAVOS afterloader. Source positioning was characterized by means of autoradiographs acquired for three different loading patterns and three 192Ir sources over a period of 5 months. Additionally, the actual source path was determined by means of a series of planar kV images for different dummy cable positions. The first position‐dependent correction method consists of locally modifying the radius of the reconstructed source path according to the measured offsets. The second method, recommended by Varian, simulates a bidirectional movement of the source during applicator reconstruction to compensate for positioning errors.ResultsAutoradiographs showed a quasi‐linear increase of the dwell position offsets, with a negligible error at the tip and a value close to 3 mm at the end of the ring. This result, consistent with a circular wire movement with an effective radius 0.5 mm larger than the nominal value, was in agreement with the observations from the kV images. After implementation of the position‐dependent correction methods, residual positioning errors for the two methods resulted in a mean value (±1 SD) of 0.0 (±0.3) mm, and a range of [−0.7 mm, 0.7 mm].ConclusionThe two tested methods for applicator reconstruction with position‐dependent source offset corrections were able to successfully correct the positioning errors. The method recommended by the manufacturer had the additional advantages of a more straightforward implementation and the potential for use in other applicator types.
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  • 2025


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  • 2025


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  • 2025

    The mitochondrial proteome arises from dual genetic origin. Nuclear-encoded proteins need to be transported across or inserted into two distinguished membranes, and the TOM complex represents the main translocase in the outer mitochondrial membrane. Its composition and regulations have been extensively investigated within yeast cells. However, we have little knowledge of the TOM complex composition within human cells. Here, we have defined the TOM interactome in a comprehensive manner using biochemical approaches to isolate the TOM complex in combination with quantitative mass spectrometry analyses. Within these studies, we defined the pleiotropic nature of the human TOM complex, including new interactors, such as TRABD. Our studies provide a framework to understand the various biogenesis pathways that merge at the TOM complex within human cells.
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